Gastrointestinal Safety of Direct Oral Anticoagulants: A Large Population-Based Study
نویسندگان
چکیده
منابع مشابه
Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism: multicentre, population based, observational study
Objective To determine the safety of direct oral anticoagulant (DOAC) use compared with warfarin use for the treatment of venous thromboembolism.Design Retrospective matched cohort study conducted between 1 January 2009 and 31 March 2016.Setting Community based, using healthcare data from six jurisdictions in Canada and the United States.Participants 59 525 adults (12 489 DOAC users; 47 036 war...
متن کاملRisk of gastrointestinal bleeding associated with oral anticoagulants: population based retrospective cohort study
OBJECTIVES To determine the real world safety of dabigatran or rivaroxaban compared with warfarin in terms of gastrointestinal bleeding. DESIGN Retrospective cohort study. SETTING Large administrative database of commercially insured people in United States from 1 October 2010 through 31 March 2012. PARTICIPANTS Enrollees with a prescription of warfarin, dabigatran, or rivaroxaban between...
متن کاملReversal of direct oral anticoagulants
Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a major concern in clinical practice. After DOACs were introduced and became widely used as an alternative for vitamin K antagonists in the management of venous thromboembolism and nonvalvular atrial fibrillation, the need for effective reversal agents has increased, particu...
متن کاملComparative effectiveness and safety of oral anticoagulants for atrial fibrillation in real-world practice: a population-based cohort study protocol
INTRODUCTION Anticoagulants are arguably the most important drug family of all, based on the frequency and duration of their use, and the clinical importance and frequency of benefits and harms. Several direct acting oral anticoagulants (DOACs) have recently joined warfarin for the treatment of atrial fibrillation, with a resultant significant expansion in use of oral anticoagulants (OACs). Our...
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آزمون انطباقی رایانه ای (cat) روشی نوین برای سنجش سطح علمی دانش آموزان می باشد. در حقیقت آزمون های رایانه ای با سرعت بالایی به سمت و سوی جایگزین عملی برای آزمون های کاغذی می روند (کینگزبری، هاوسر، 1993). مقاله حاضر به دنبال آزمون انطباقی رایانه ای برای ترجمه می باشد. بدین منظور دو پرسشنامه مشتمل بر 55 تست ترجمه میان 102 آزمودنی و 10 مدرس زبان انگلیسی پخش گردید. پرسشنامه اول میان 102 دانشجوی س...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2017
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2016.12.018